Folate is one of the best-established nutrients in early pregnancy. NHS guidance recommends folic acid before pregnancy and until 12 weeks to help reduce the risk of neural tube defects, including spina bifida. Ideally supplementation should begin at least three months before conception.
The neural tube closes very early, typically by around week 6, often before someone knows they are pregnant. That timing is the central reason preconception nutrition matters. Yet only around 1 in 5 women in England took folic acid before pregnancy in 2023–24, with the lowest uptake in the most deprived areas.
Some genetic variations are involved in folate metabolism and the wider one-carbon network (folate, B12, choline). HerCode does not replace NHS folic acid guidance. It helps personalise nutrition support around the folate-related pathways your body uses every day.